Transparent 340B administration,
live and working.

A single, streamlined interface for covered entities and contract pharmacies—responding to good-faith inquiries, resolving duplicate discounts, and keeping every eligible dollar in your program.

OptimSync340B in sync

What the platform does

Full split-billing administration, with the economics in plain view.

Automate claims processing

Every 340B claim validated in real time.

Claims are checked the moment they land. AI-driven matching flags duplicate and ineligible claims automatically, and direct wholesaler and TPA integrations keep your split-billing accurate without the manual reconciliation.

AI-driven matchingDuplicate detectionWholesaler & TPA integration

Complete financial visibility

See exactly what your program earns—and what you pay us.

Real-time dashboards track savings as they accrue. Transparent audit trails and reconciliation tools mean nothing is skimmed off the top and nothing is hidden. You forecast performance from numbers you can trust.

Live savings dashboardAudit trailsReconciliationForecasting

Specialized support

A dedicated 340B team, not a ticket queue.

You work with people who know 340B. We provide compliance guidance, stand with you through audits, and train your staff so program integrity is protected long after go-live.

Compliance guidanceAudit assistanceStaff training

How the platform works

Follow every product, payment, and reimbursement.

See how OptimSync connects the manufacturer, covered entity, contract pharmacy, wholesaler, payer, and patient across the full 340B contract-pharmacy workflow.

340B Contract-Pharmacy Model

OptimSync Platform

How product, funds, and reimbursements move between the manufacturer, covered entity, contract pharmacy, and payer — with OptimSync sitting at the center of every transaction.

1Product shipment5Wholesaler replenishment1Prescription3Replenishment PO4Replenishment PO5CE pays wholesaler7Reimbursement (minus fees)6Reimbursement(minus contract pharmacy fee)7340B ceiling price discount2Rebate2Pharmacy reimbursement2Patient copaymentMedicare Part DClaims Data RepositoryEffective 4Q26OptimSyncPlatformWholesalerDistributorCovered Entity(CE)Health SystemManufacturerDrug MakerContract PharmacyDispensing SiteThird-party Payer/ Health PlanInsurerPatientFlow legendProduct movementFinancial flowContractual relationshipGlossaryCECovered EntityAWPAverage Wholesale PricePOPurchase OrderMFPMaximum Fair PriceNumbered badges mark the order each step occurs in.Hover a legend row to trace a single flow.

Figure 1. OptimSync workflow

Your data, live and yours

Log in and see your own program, accurate to the claim.

Every covered entity gets secure, real-time access to its own data—no black box, no waiting on a vendor report. Watch savings accrue, track every claim to resolution, and ask questions in plain language with the built-in AI assistant.

  • Program savings
  • Total collected
  • Pharmacy profit
  • Capture rate
  • Qualified claims
  • Utilization rate

340B ESP & Truzo

Manufacturer submissions, handled end-to-end.

Manufacturer policies require contract-pharmacy claims to be submitted to ESP and Truzo, within compliance windows, to preserve 340B pricing. OptimSync runs both workflows for you—your team stays hands-off.

340B ESP

We submit eligible claims to ESP for you and track every one to resolution, so no eligible 340B claim falls outside its NDC compliance window.

  • Eligible claims submitted for you
  • NDC compliance-window tracking
  • Every claim tracked to resolution

Truzo

Truzo is the manufacturer platform for validating 340B contract-pharmacy claims. OptimSync submits on your behalf and runs the end-to-end workflow.

  • Pharmacy designations & TPA authorizations managed
  • Eligibility validated before submission
  • Hands-off for your team

Referral capture

Compliant 340B revenue you aren’t capturing today.

Eligible specialty prescriptions written beyond your walls are usually missed. Our referral capture finds them, verifies each against your policies, and routes them for savings—built into the platform.

See how referral capture works

A boost for covered entities

Manage your program with confidence.

Confident compliance

Audit-ready processes and clear records keep your program defensible every day, not just at audit time.

Program integrity

Duplicate-discount and eligibility controls protect the savings your organization depends on.

Manufacturer coordination

Respond to good-faith inquiries and resolve Medicaid duplicate discounts from a single interface.

A real feedback loop

Share what your program needs and see it reflected in how the platform works for you.

For contract pharmacies

A unified view built on a claims data engine like no other.

Purpose-built to maximize the value of your 340B program and surface compliance risk early—drawing on more than twenty independent data sources for validated, real-time insight.

Operations

Unified claims management and workflow automation that cut manual work and keep every dispense accounted for.

Finance & savings

Maximized reimbursement and recovery of missed eligible claims—more value captured from every 340B prescription.

Compliance

Centralized documentation and audit-ready records that hold up to scrutiny across every relationship.

Analytics & insights

Performance tracking and actionable data built on gold-standard, validated claims information.

See it against your own program

Ready to see what your 340B program could keep?

Request a demo